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Mounjaro treatment and how it works
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Mounjaro® treatment and how it works

The National Institute for Health and Care Excellence (NICE) recommends tirzepatide (Mounjaro®) for the management of obesity for certain patients. On this page we break down how this treatment works, how it benefits, and how to manage your equipment when taking it.

What is Mounjaro®?

What is Mounjaro®?

Mounjaro® is a once-weekly injection used for the treatment of type 2 diabetes in adults and/or weight loss, weight management. It contains an active substance called tirzepatide (tir-zep-a-tide). Mounjaro® is what’s called a GLP-1 receptor agonist. This means it works in your body to mimic the action of two naturally occurring hormones; glucagon-like peptide 1 (GLP-1) and glucose-dependent insulinotrophic polypeptide (GIP) too. Mounjaro® slows the emptying of your stomach, so that you feel fuller for longer.

Mounjaro® is a weekly injection available in five doses. Your dose will depend on where you are in your treatment journey. The starting dose is 2.5mg. This increases in increments of 2.5mg until you reach 15mg.

It is important to continue to follow the advice on diet and exercise given to you by your healthcare professional.

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How Mounjaro® works

A few of the ways Mounjaro® helps your body include:

  • 1. Releasing insulin when your blood sugar is high, if you’re living with type 2 diabetes.
  • 2. Reducing how much food you eat.
  • 3. Slowing down how quickly food leaves your stomach. This lessens over time.
  • 4. Regulating fat utilisation.

How Mounjaro® helps reduce your body weight

  • 1. Improves insulin sensitivity.
  • 2. Regulates your appetite, giving you a sense of satiety (‘fullness’) & makes you feel less hungry.
  • 3. Reduces food cravings for fast-food fats, sweets, carbohydrates & starches.
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How Mounjaro® works

When to use Mounjaro®

  • You can use your pen at any time of the day, with or without meals.
  • Use Mounjaro® on the same day each week.
  • To help you remember, when to use Mounjaro®, you may wish to tick the day of the week when you inject your first dose on the box that your pen comes in, or mark it on a calendar.
  • If necessary, you can change the day of your weekly injection, as long as it has been at least 3 days since your last injection.
  • After selecting a new dosing day, continue with once-a-week dosing on that new day.
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Take a look at this video to see how to use your Mounjaro® pen. Click to play.

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Caring for your pen

Caring for your Mounjaro® pen

  • Don’t drop your pen or knock it against hard surfaces
  • Keep your pen away from liquids
  • If you think that your pen may be damaged, don’t use it or try to fix it. Use a new pen
  • Keep the pen cap on until you are ready to inject, to reduce the risk of infection. Your pen will not be sterile if it is stored without the cap, if you pull the pen cap off and put it on again, or if the pen cap is missing
  • Store the Mounjaro® pen in the fridge between 2 and 8°F (36 and 46°F). Do not freeze
  • Store in the original, unopened packaging

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